Antibiotic treatment of gonorrhoea--clinical evidence for choice.

Introduction The clinician's choice of treatment for gonorrhoea focuses on clinical efficacy, patient acceptability and toxicity. These criteria inevitably encompass consideration of in vitro antimicrobial sensitivities, the pharmacokinetic properties of candidate antimicrobials, anticipated compliance, cost-effectiveness, ease of administration, patient's age, pregnancy and previous adverse drug reactions. Concomitant infection with other sexually transmitted pathogens should be sought and managed appropriately.